| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 8/25/2022 |
@
Cheyenne-Eagle Butte/Tiospaye Topa #102
|
W 58-6 | Cheyenne - Eagle Butte School | |
| 9/2/2022 |
vs
Pine Ridge #98
|
W 57-0 | Winnebago High School | |
| 9/9/2022 |
vs
St. Francis Indian #88
|
W 60-0 | ||
| 9/16/2022 |
vs
Todd County #8
|
L 20-36 | ||
| 9/23/2022 |
@
Tiospa Zina #54
|
W 60-6 | Tiospa Zina Tribal School | |
| 9/30/2022 |
@
Flandreau Indian #129
|
W 48-0 | ||
| 10/6/2022 | vs Omaha Nation, NE #104 | W 52-0 | Winnebago High School | |
| 10/14/2022 |
@
Mahpíya Lúta #26
|
L 42-48 | Red Cloud Indian School | PARENT DAY |
| 10/25/2022 |
vs
Little Wound #56
|
W 40-0 | All Nations A - State Quarterfinal | |
| 10/29/2022 |
vs
Todd County #8
|
L 24-28 | Todd County High School Todd County High School | All Nations A - State Semifinal |