| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 8/27/2021 |
vs
Mediapolis #178
|
L 22-44 | Wapello Athletic Complex | |
| 9/3/2021 |
vs
Louisa-Muscatine #321
|
W 45-0 | Louisa-Muscatine High School | |
| 9/10/2021 |
vs
Columbus #302
|
W 52-21 | Wapello High School | |
| 9/17/2021 |
@
Pekin #332
|
W 35-0 | Pekin Community High School | |
| 9/24/2021 |
vs
Lisbon #112
|
L 14-28 | Wapello High School | |
| 10/1/2021 |
@
Highland #273
|
W 34-21 | Highland High School | Homecoming |
| 10/8/2021 |
vs
Alburnett #241
|
W 48-12 | Wapello Athletic Complex | |
| 10/15/2021 |
@
North Cedar #322
|
W 48-6 | Doug Jackson Field | Senior Night |
| 10/22/2021 |
vs
North Tama #102
|
L 22-23 | Wapello Athletic Complex | A - First Round |
