| Date | Opponent | Result | Location | Caption |
|---|---|---|---|---|
| 8/26/2022 |
vs
Watertown #94
|
W 26-3 | SDSU - Dana J. Dykhouse Stadium | |
| 9/2/2022 |
vs
Pierre T.F. Riggs #5
|
L 0-48 | SDSU - Dana J. Dykhouse Stadium | |
| 9/10/2022 |
@
Huron #114
|
W 24-2 | Tiger Stadium | |
| 9/16/2022 |
vs
Spearfish #97
|
W 33-20 | SDSU - Dana J. Dykhouse Stadium | |
| 9/23/2022 |
@
Douglas #136
|
W 40-6 | Douglas High School | Homecoming |
| 9/30/2022 |
vs
Yankton #72
|
L 27-38 | Dana J. Dykhouse Stadium | Homecoming |
| 10/7/2022 |
@
Aberdeen Central #66
|
L 3-20 | Gene Brownell Complex | |
| 10/14/2022 |
@
Harrisburg #25
|
L 7-41 | Harrisburg High School | |
| 10/20/2022 |
vs
Mitchell #106
|
W 35-21 | SDSU - Dana J. Dykhouse Stadium | Senior Night |
| 10/27/2022 |
vs
Yankton #72
|
L 14-49 | Crane-Youngworth Field | Class 11AA - State Quarterfinal |
